Amoxicillin trihydrate 3.44 g
Cloxacillin Benzathine (micronized). 3.83 g
Excipients q.s 100 g
Intramammary suspension in dosing syringe ready for use.
It is used for the anti-infectious treatment of clinical mastitis in cows during the dry period and, especially, in cows whose lactation curve shows that they are undergoing or might have undergone some subclinical mastitis process. Effective against bovine mastitis-related Gram-positive and Gram-negative microorganisms.
AmoxiRhein SB has 2 relevant effects: It is resistant to beta-lactamase (penicillinase) and it shows bacterial activity, together with amoxicillin.
As it is an oil-based non-soluble benzathine salt , it can be maintained for long periods of time in glandular tissues.
Susceptible gram-positive germs: Staphylococcus aureus producing and non producing penicillinase. Staphylococcus epidermidis, Staphylococcus caprae, Staphylococcus cromogenes, Streptococcus agalactiae, Streptococcus uberis, Streptococcus disagalactiae Corynebacterium pyogenes Susceptible gram-negative germs: Escherichia coli, Klebsiella spp, Haemophilus spp
DOSAGE AND USE :
This product is administered 60 days prior to labor, when the dry process starts.
After the last milking process and once the udder is washed and disinfected, administer all the content of a syringe in each affected teat, then, apply some soft massage to the teat for a better distribution of the medication.
Use 2 syringes per teat area in cows showing a cell rate higher than 500 000 somatic cells/ml during the dry process. (Regarding this dosage scheme, no withdrawal period has been established in milk, therefore, it should be analyzed before sending it for industrialization or human consumption purposes).
A single dose is indicated.
If no proper dry process has been conducted and it is necessary to milk again, a second dose will be applied.
AmoxiRhein SB must only be administered at the beginning of the dry process.
Do not apply within a period of 60 days prior to labor. Do not administer to cows during milk production process.
Before administering the content in the syringe, milk and disinfect the affected teat.
Do not mix with other substances or solutions in the same syringe or teat canal.
Do not use when penicillin-hypersensitivity cases are detected. Apply the total content of the intramammary syringe.
Do not administer when penicillin hypersensivity cases are detected.
Do not reuse the container for subsequent use. Keep in a fresh and dry place. Keep out the reach of children. Keep proper hygiene conditions before, during and after the administration of the product.
Any suggested doses and warnings shall, in all cases, be at the veterinarian’s discretion.
Check that the product is properly sealed and that its storage conditions before use are correct.
Keep in original container, at a temperature ranging between 5 and 25ºC. Avoid direct sun light contact with the product.
People allergic to beta-lactamic drugs must not have direct contact with the product.
Avoid contact with the product during the administration process. If any accidental exposure is produced, wash with tap water and soap.
The operator must wear mask, goggles, overall and rubber gloves.
Do not apply within a period of 60 days prior to labor.
If 60 days have not elapsed between the administration of the product and labor, the milk must be sampled in order to detect the presence of any antimicrobials until obtaining two negative consecutive samples, before sending it for human consumption.
Thirty days must elapse between the administration of the product and the animal slaughtering process.
Milk withdrawal period: 12 hours.
5,5 g intramammary syringes